Weight Loss

Who We Are

We are a weight loss center designed and run by a physician who is an Obesity Medicine specialist

At Inland Empire Weight Loss, you will find a multifaceted weight loss program designed and run by a board certified Obesity Medicine specialist. Our staff is trained in the use of a variety of techniques to help you achieve your weight loss goals. Know that we are not just a clinic where you can get a diet pill, we are a full spectrum weight loss center.

Compare our program to others such as Weight Watchers and Nutrisystem as well as programs where you only see a nurse practitioner. If there is no medical doctor on the website, then it is likely that there is no physician in the office. It is well known that appetite suppressants all work for a short time. Wouldn’t you like to have a program where you can know what to do after the medication stops working? We pride ourselves on delivering long term, effective, safe, and healthy results to all our patients. Continue reading to find out more about us. We look forward to meeting you.

How We Help You

Our clinic focuses on a multipoint program that addresses all aspects of weight loss.


The cornerstone of any successful weight loss program is behavioral management. Utilizing a combination of strategies that involve motivational interviewing and cognitive behavior therapy we can address many common problems that are present in overweight patients. Additionally, treatment of any underlying psychiatric illnesses with appropriate medications allows for better weight loss and keeps the individual from using food as their psychiatric drug of choice.


We use a combination of education and medical grade meal replacements to facilitate weight loss. Items that we offer include shakes, bars, and meat products. Each meal replacement assures an appropriate amount of protein for healthy weight loss and avoidance of hunger. We also give dietary advice on foods that you may prepare or purchase. The education we provide helps you to keep your weight off for the long term.

Appetite Suppressants

We provide appetite suppressants or "diet pills" to most of our patients. There are a variety of different medications to choose from depending on the specific condition of each person. These medications can range from phentermine which has been in use for over 50 years to the newer medications such as Contrave, Belviq, Saxenda, and Qsymia. Anorectic medications help you to avoid hunger, and enables dietary behavioral change. They may also help to increase your metabolic rate to help in weight loss.

Lipotropic and B12 Injections

Many patients notice a metabolic boost and improved weight loss with a weekly injection. Our lipotropic injections contain a blend of methionine, inositol, choline, vitamin B12, L-carnitine, and adenosine. The combination can help to increase energy levels and encourage fat metabolism. Ask to have this added to your regimen.

Or you can elect for B12 injections alone. Some people have vitamin B12 deficiencies due to an inability to absorb the vitamin or as a side effect of taking certain medications. We can perform a formal analysis of your ability to absorb vitamin B12.

Weight Loss For Women

Common weight related problems associated with women include weight gain after pregnancy, peri-menopausal weight gain, and cyclical eating patterns related to both normal and abnormal menstrual cycles. There is also a greater likelihood of eating disorders such as binge eating disorder and atypical depression which is associated with mood related eating. Additionally, insomnia and anxiety can increase levels of hunger and decrease activity levels. It is time for you to feel good again. Our approach is to provide specific treatments for each of these problems. Treatments can include bioidentical hormone treatments, which help with anxiety and insomnia characteristic of peri-menopausal women; treatment of impulsive behavior patterns such as binge eating disorder; or treatment of more common ailments such as depression and anxiety using medications that do not cause weight gain. If you have been unhappy with your medications causing you weight gain, then we are here to help.

Weight Loss for Men

Weight gain in men often follows “andropause” which is associated with a decrease in testosterone in older men. Similarly, testosterone levels can decrease in men who suffer from problems of obesity at a younger age range. Typically, men will experience a decrease in strength, motivation, ambition, focus and libido. Some may even suffer from ED or erectile dysfunction. The decrease in testosterone can also be associated with the onset of diabetes or insulin resistance. Treatment for the low levels of testosterone can either come in the form of testosterone replacement therapy using testosterone injections, topical testosterone formulations, or pills that can boost testosterone levels. We can also offer medications that affect the way testosterone is processed in the body. This results in maximizing the effect of the testosterone which you have. Get your life back and regain your strength and motivation.


Many of our patients also have medical and psychological problems as well. It is extremely important to optimize the medications that are used for these problems to assure they are not causing a gain or failure to lose weight.


There is no doubt that exercise helps in the weight loss process. We encourage all of our patients to exercise regularly. However, we regularly find people who are exercising in the wrong way to promote weight loss. Often by making subtle changes to your exercise program, we can get you back on the right track to losing weight.


We find that regularly scheduled visits, usually at 2 week intervals, are important in keeping people on track towards their weight loss goal. We have yet to meet someone who does not stray from the program at some point. By having you come back regularly, we provide guidance and emotional support to solve problems that come up in many individuals program.


We realize that most of our patients work and scheduling is important for them. Between our three providers, we have two mornings that start at 7:00 am. If you work locally, then we offer a lunch clinic. Additionally, our clinic has early evening hours until 6:00 pm two days per week so that you can come in on your way home. We pride ourselves on our customer service and we are constantly working on making sure that your experience is positive and efficient.


When you have reached your goal, we will not forget about you. Because each person is different, the long term strategy for each individual is also different. There are many options to maintain long term weight loss success including tapering off of all therapies, maintaining less frequent visits, management of episodic weight regain, maintaining long term use of appetite suppressants, or long term management of psychiatric medications. There is no one answer to how maintenance is achieved. When you have achieved your goals, we will construct an appropriate maintenance plan for you.


We offer programs starting at just $74 for return visits and this includes 2 weeks of medication. This is just $37.00 per week to see an Obesity Medicine Specialist! If you want to come in monthly, then our pricing starts at just $84 per month. This is equates to just $19.39 per week.* An intake visit starts at $114. See our coupon page for our current offers. We are also proud to offer Care Credit. Please call for further information on Care Credit and our pricing.

We also accept PPO and Medicare insurance when you have health conditions related to your weight. To qualify, you need a Body Mass Index (BMI) greater than 25 for PPO insurance or greater than 30 for Medicare with weight related health conditions. Partial coverage may be available if you do not meet these criteria. Even if you have HMO/IEHP or even Kaiser, your laboratory workup is typically covered by your insurance. Please call for more details.

Compare us to Weight Watchers

The American Medical Association has declared that Obesity is a disease and numerous other medical societies agree. Wouldn’t you want a doctor to take care of your medical problem rather than a counselor? Look at everything you get with Inland Empire Weight Loss that you cannot get with Weight Watchers:

  • Weight Loss program designed and run by a board-certified Obesity Medicine Specialist
  • See a medical doctor or physician assistant at each visit
  • Receive anti-obesity medications (diet pills) with your visit
  • Meal replacement programs offered
  • Receive an exercise prescription and have this modified as the program progresses
  • Receive individualized care
  • Receive behavioral counseling from a nationally recognized instructor
  • Programs as low as $19.60 per week* including weight loss medication
  • Program is often covered by insurance, including PPOs and Medicare

*Assumes our basic program with 30 day supply of anorectics and based on monthly return visits. Actual visit cost is $84.

Compare us to Nutrisystem

A weight loss program is more than just delivering pre-prepared meals to your door. All diets work for a finite period of time before the eventual plateau sets in. Find out how to maximize your weight loss and learn what you are really capable of. When you see a board certified Obesity Medicine Specialist at Inland Empire Weight Loss, besides all of the items listed to the left under Weight Watchers, look at how our weight loss program stacks up to Nutrisystem:

  • Meals replacements for 2 meals starting at just $8 per day
  • Counseling from a doctor or physician assistant on how to use your foods
  • Treatment of underlying and related health conditions
  • Learn how conditions that you may already have such as sleep apnea and depression are affecting your ability to lose weight.
  • Receive a full laboratory evaluation as well as a hormonal analysis to determine what is keeping you from losing weight.
  • Receive weight loss medications from an experienced Obesity Medicine Specialist

Pediatric Weight Loss

Getting kids to lose weight is very different than getting adults to lose weight.

Getting kids to lose weight is very different than getting adults to lose weight. First of all, obesity in kids is measured differently than it is in adults. Kids get insulin resistance and diabetes just like adults but the laboratory findings are different and they need to be assessed by a health care provider trained in this area. We stress that there needs to be changes in the whole family when it comes to things such as eating and exercise.

Children’s relationship to foods is often still developing and strongly shaped by the environment that surrounds the child. We help to properly assess your child in a sensitive way for problematic weight and weight related health programs and then we will propose a program that your child will be excited about participating in. If you are worried that your child has a problem with their weight or if they have been told to lose weight by their pediatrician, then we are here to help.

Obesity Medicine

An Obesity Medicine trained physician will not only help you to lose weight but will be an expert in recognizing and treating your weight related conditions

Obesity Medicine is new specialty that is governed and credentialed through the American Board of Obesity Medicine. Organizations that provide educational support and recognition to the field of Obesity Medicine can be found here.

An Obesity Medicine trained physician will not only help you to lose weight but will be an expert in recognizing and treating your weight related conditions. This is important because as you lose weight, your medications that you have been taking for your weight related condition will frequently change.

Common problems that are seen in an obesity medicine clinic can include but are not limited to:

(This is only a partial list)


Please come to your appointment with this filled out to speed up the check in process.

You can prefill this out or review it at home to understand the risks and benefits to the weight loss process.

This packet is used for our non-weight loss patients. Please come to your appointment with this filled out to speed up the check in process.

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Corporate Program

Create a Healthier Work Environment

If you are a Human Resources manager or a corporate executive who is looking to lower health care costs within your organization by reducing the chronic disease burden among your employees, then Inland Empire Weight Loss would like to help. We offer a wellness program designed to reduce and improve obesity related chronic conditions through improvements in lifestyle, diet, and exercise. We can work with an individual’s current health care provider to design a program that improves overall health and reduces their medication burden.

If your company offers a shared or full risk environment in providing health care benefits to your employees, then a wellness program such as ours will offer immediate benefits in reducing healthcare pharmacy, medical, and hospital claims. Even if you are not in a shared/full risk environment, employees who are healthier have a decreased disease burden which results in a lowering of medical claims loss and a decrease in corporate health insurance rates. Additionally, if your employees have a reduced weight and improvements in their health, there will be a decrease in absenteeism and an increase in productivity.

Dr. Knopke is double board certified in Obesity Medicine and Family Medicine. He is a leader in the field of Obesity Medicine. He has been elected and currently serves as a member of the Board of Trustees for the Obesity Medicine Association (OMA) and is an Assistant Professor in Family Medicine at the University Of California Riverside School Of Medicine. Additionally he is a member of many other related Medical Associations. He has spoken to and taught other medical professionals both locally and nationally on topics related to Obesity Medicine. He also offers a 4th year elective rotation to UCR medical students interested in pursuing a career in the field of Obesity Medicine. He is an active participant in designing continuing medical education (CME) programs on the topic of obesity medicine through OMA.

Further information on Dr. Knopke can be found on his LinkedIn page. Interested parties are invited to send an email to Dr. Knopke at drknopke@inlandempireweightloss.com or to call the office directly at 951-774-2723 and ask to speak to Dr. Knopke about options for the corporate program. Dr. Knopke can meet individually with HR managers or other corporate decision makers on a one on one basis to discuss options should there be interest in our program. We look forward to making your employees healthier.


Find your program

One of the big advantages of choosing a clinic that is run by a board certified Obesity Medicine Specialist is that we can take care of a wide spectrum of medical needs. Whether you have recently gained 15-30 pounds through a pregnancy and you have not been able to lose the weight or you are currently taking multiple medications to treat chronic health conditions such as diabetes or hypertension, we are here to help. We even see people after bariatric surgery who have plateaued in their weight loss. Read about our pricing structure below and decide which program is best for you. If you are cost sensitive, please let your healthcare provider know so that we can shape a program that is right for you. Our least expensive option is our Basic program with an added supply of phentermine to make it last for a month. This comes to less than $19.79 per week! You will not find a better price in the Inland Empire. Our prices as listed are those for established/new patients. Please see our specials page for our current offers. For your convenience, we also accept CareCredit.

Insurance Accepted

PPO, EPO, HSA/FSA, Medicare/Tricare

If you have a fee-for-service type health insurance and multiple medical problems, then this is the best option for you. Did you know that most of the listed insurance plans have at least some coverage for weight loss? Let us evaluate you for your qualifications to use your health insurance. We can usually find a way to make it work.

  • For those with PPO, EPO, HSA/FSA or Medicare\Tricare type of insurance
  • Significant savings can be achieved over our typical rates*
  • Typical eligibility criteria include having a weight related health problem and a BMI of at least 27 or a waist circumferance that meets criteria for obesity.
  • Examples of weight related conditions can be found here.
  • Qualifying is typically easier than you think.

No Insurance? No problem. Here is our:

Cash Pricing

Basic $74/$114*

This is our best value. It is intended for the person who has recently gained weight and has not able to lose it on their own. Carrying extra weight over many years exposes you to multiple health risks. This is especially so if you have someone in your family with weight related health problems. Allow us to evaluate you for your health risks and let us show you how to lose the weight and feel great.

  • For individuals looking to lose 15-30 pounds
  • Have no current major health problems
  • Reduce future health risks associated with having extra weight.
  • Feel rejuvenated and increase your energy level through weight loss.
  • Start using your skinny jeans again!

Expanded $94/$139*

This is our most popular level. We find that many of our patients have struggled to lose weight even with an appetite suppressant. Often we see patients from other weight loss clinics who were told to stop taking their appetite suppressent when they stopped losing weight. We see things differently. The appetite suppressant is a tool to achieve a result but it is not the only tool we have! There are many ways to break through a plateau. Ask us how. This is what we do!

  • Our most popular level
  • Address 1 additional established weight related problem during the visit
  • Get to the root causes of weight loss failure when an appetite suppressant alone stops working
  • Common examples of treated problems include sleep, anxiety, and pre-diabetes.

Expanded Plus $114/164*

Many of our patients have multiple weight related complications. At this level, we will address 2 additional problems related to your weight. Addressing weight related problems in an integrated and coordinated way is the best way to get to the root cause of weight gain and get you back on the pathway to a more healthy lifestyle.

  • Integrate and coordinate care of seperate problems
  • Address 2 additional established weight related problems during the visit
  • Expedite your weight loss by addressing multiple topics
  • Common examples of treated problems include sleep, anxiety, and pre-diabetes.

Complex $134/$189*

This is where we really shine. If you have several health problems and you are taking multiple medications, we can help. Do you have diabetes and you are on insulin? We can get your blood sugar down and take you off of your insulin. Have the costs of your medications become too much? Have you already had bariatric surgery and you have stopped losing weight? We can help you.

  • For complex patients taking multiple medications
  • Manage 3 additional established medical problems related to your weight or...
  • Manage 1 new weight related problem with up to 1 established problem
  • Decrease your chronic disease burden
  • Achieve your goal of decreasing the number of medications that you take

All Programs Come With:

Established Visits

  • Body composition analysis to determine your fat, muscle, and water mass at each visit
  • Progress check to evaluate for ongoing problems
  • 2 weeks of appetite suppressants**
  • Counseling to facilitate behavioral change
  • Exercise guidance

Initial Visit - additionally includes:

  • Complete history and physical to fully evaluate your current health status
  • Initial workup on health issues that may affect your ability to lose weight
  • Detailed start-up instructions
  • Laboratory orders
  • Instructions on starting appetite suppressants


Phentermine - 1 month supply $12

Each visit comes with a 2-week supply. Extend this out to a month for only a little more. Combine this with our basic program to get our lowest price, just $19.79 per week!

EKG $35

Getting an EKG as a component of your initial evaluation can be important to help identify cardiac issues that may put you at risk. We do recommend that you get this prior to starting on the program.

Lipotropic injections $22

These are our most popular injection. Each comes with a mixture of vitamins designed to mobilize fat stores and increase energy levels. Try these at other centers and they can be painful on injection. Our proprietary formula is designed to minimize the discomfort that is associated with this formulation.

B12 injections$16

Many people lack the ability to absorb vitamin B12 or they take medications which makes absorption difficult. Others like the effect of a little extra B12 in their system and feel a boost of energy. Ask us about this and we can tell you if this is right for you.

Meal replacements~$2.25

For many of our patients, this is the "secret formula" to their success. We carry a wide range of products ranging from soups, bars, shakes, and meat sticks. All are formulated to provide you with an increased supply of protein and low delivery of carbohydrates. If you have particular needs in your meal replacements, just ask us and we can help you to decide if this option is right for you.

Extra Problem$30

Do you have more medical problems than the average bear? Don't worry, we won't hold it against you. Let us save you a trip to the doctors office and allow us to take care of that extra problem here.

Bioidentical Hormone Replacement Therapy

We find that many of our patients, both men and women, suffer from hormone related problems as a consequence of their excess weight. Like many problems we see related to obesity, unhealthy hormone levels are both a consequence and a cause of weight problems. Often, by subtle alterations of your hormones, we can enable weight loss where you have struggled before. Ask us how this can help you.

Complete BHRT evaluation on follow-up$149

Complete evaluation on a new BHRT visit $299

*Our Basic, Expanded, Expanded+ and Complex visits are also defined by time with the provider on an established/new basis as follows: Basic is typically 10/20 minutes, Expanded is typically 15/30 minutes, Expanded+ is typically 20/40 minutes, and Complex is typically 25/50 minutes. If there are additional problems that are required to be managed during the visit, these will be charged on an established/new basis at $30/$60 per problem. Addressing additional problems may be limited by time and safety as determined by the provider.

**Appetite suppressants dispensed upon physician approval. A prescription for an alternative appetite suppressant may be given in lieu of dispensing a medication. Savings with insurance assumes you have satisfied your deductable. Coinsurance levels vary. Please ask for more details if you have questions.

For Providers

Inland Empire Weight Loss is currently accepting consultation requests in the area of Obesity Medicine.
Inland Empire Weight Loss is currently accepting consultation requests in the area of Obesity Medicine. Dr. Knopke is double Board Certified in the field of Obesity Medicine by the ABOM and in Family Medicine. The specialty board of Obesity Medicine was established in 2011. Further information on this board can be found here. Upon request of a consultation, you as a provider will receive a consultation letter from Dr. Knopke or Lesley Laird, PA-C. If there are questions in regards to the plan, Dr. Knopke will be more than happy to discuss any concerns you may have on the phone. For an overview of the assessment and treatment techniques, I would refer you to the OMA Obesity Algorithm. Our aim is to diminish the burden of chronic disease in the individual affected by Obesity. We accept most major PPO health insurances as well as Medicare. We accept consultations for the following requests:

  • Weight loss (Adults and Children)
  • Diabetes and other diseases related to insulin resistance such as:
  • Metabolic syndrome/Prediabetes/Insulin Resistance
  • PCOS
  • Hypertension
  • Fatty liver, NAFLD/NASH
  • Hyperlipidemia
  • Pre and post-bariatric surgical evaluations
  • Migraine headaches (tends to improve with weight loss and dietary change)
  • Obesity related psychiatric disorders such as:
  • Binge Eating Disorder
  • Night Eating Syndrome
  • Major Depression (when related to obesity)
  • Generalized Anxiety Disorder (when related to Obesity
  • Bipolar Disorder (when related to Obesity)
  • Addictions to food/carbohydrates
  • Obstructive Sleep Apnea (to manage their weight)
  • Osteoarthritis: weight loss for symptomatic improvement and to help with preoperative weight loss for total knee and hip arthroplasty.
  • Ventral hernias that require preoperative weight loss
  • Prepregnancy weight loss and help in Obesity related fertility issues (such as PCOS)

Dr. Knopke is a leader in the field of Obesity Medicine. He has been elected and currently serves as a member of the Board of Trustees for the Obesity Medicine Association (OMA) and is an Assistant Professor in Family Medicine at the University Of California Riverside School Of Medicine. Additionally he is a member of many other related Medical Associations. He has spoken to and taught other medical professionals both locally and nationally on topics related to Obesity Medicine. He also offers a 4th year elective rotation to UCR medical students interested in pursuing a career in the field of Obesity Medicine. He is an active participant in designing continuing medical education (CME) programs on the topic of Obesity Medicine which are designed to educate other Obesity Medicine providers around the country on various topics in Obesity Medicine. He is also an instructor for the OMA for their board preparatory course to help other physicians study for and pass their Obesity Medicine Board exam.

Should you have any questions about the nature of our program, Dr. Knopke can be reached at drknopke@inlandempireweightloss.com or please call the office directly at 951-774-2723 and ask to speak to Dr. Knopke.